Search results for "Natural cycle"

showing 2 items of 2 documents

Endometrial Receptivity Analysis (ERA): data versus opinions

2021

Abstract This article summarises and contextualises the accumulated basic and clinical data on the ERA test and addresses specific comments and opinions presented by the opponent as part of an invited debate. Progress in medicine depends on new technologies and concepts that translate to practice to solve long-standing problems. In a key example, combining RNA sequencing data (transcriptomics) with artificial intelligence (AI) led to a clinical revolution in personalising disease diagnosis and fostered the concept of precision medicine. The reproductive field is no exception. Translation of endometrial transcriptomics to the clinic yielded an objective definition of the limited time period …

0301 basic medicine030219 obstetrics & reproductive medicineendometrial receptivitybusiness.industryNatural cycleHormonal replacement therapyEmbryoimplantation / recurrent implantation failureDiseaseEndometriumPrecision medicineBioinformaticsAcademicSubjects/MED00905Embryo transfer03 medical and health sciences030104 developmental biology0302 clinical medicinemedicine.anatomical_structureDebate ContinuedmedicineendometriumEndometrial receptivitybusinessembryo transferHuman Reproduction Open
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Ovarian stimulation does not influence the uterine immune environment in healthy infertile women.

2019

Abstract Research question There is some controversy regarding the impact of ovarian stimulation on immune cells in women undergoing IVF. The study's aim was to determine whether ovarian stimulation affected immune uterine cells in healthy women undergoing IVF. Design This prospective cohort study included 28 patients undergoing IVF and 47 healthy oocyte donors. Endometrial biopsies were taken in a natural cycle and after ovarian stimulation. All participants had a normal karyotype, pelvic ultrasound and cervical cytology results and thyroid-stimulating hormone concentration, as well as normal glucose and insulin concentrations and inherited and acquired thrombophilia test results. Screenin…

AdultNecrosisendocrine system diseasesPopulationStimulationEndometrial biopsies Immune cell populations Natural cycles Ovarian stimulation Peripheral blood natural killer cells Uterine natural killer cellsHuman leukocyte antigenAndrologyImmune systemOvulation InductionmedicineHumansEmbryo ImplantationProspective Studieseducationreproductive and urinary physiologyMenstrual Cycleeducation.field_of_studybusiness.industryUterusObstetrics and GynecologyFOXP3biochemical phenomena metabolism and nutritionfemale genital diseases and pregnancy complicationsKiller Cells NaturalReproductive MedicinebacteriaTumor necrosis factor alphaFemalemedicine.symptombusinessInfertility FemaleDevelopmental BiologyHormoneReproductive biomedicine online
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